‘Golden Rice’: Unexpected genomic effects

15 February 2017 / A new publication has reported unintended effects in genetically engineered rice producing precursors of vitamin A, so-called carotenoids. Crossing the manipulated rice with the Indian variety Swarna led to a nasty surprise: The resulting plants showed extensive disturbance in their growth. The researchers identified several reasons for this: The new gene constructs interfere with the plant’s own gene for producing growth hormones, and the additional gene constructs were not, as intended, active solely in the kernels, but also in the leaves. This led to a substantial reduction in the content of chlorophyll that is essential for vital functions in the plants.